Next Generation Sequencing (NGS)- breaking the human genome code

So far now, it has become possible to sequence anyone’s genome cheaper and quickly with the help of latest technologies. Researchers have started gaining much into discovering the meaning of individual genomes. Though still the sequencing has not come down to an affordable price but has been sponsored mostly by the stake holders of the research projects to get into the main stream of the genomics worlds. And it has been highlighted that the individual genome sequencing would help track the rare deformities and anomalies in the gene line of human and can be engineered to treat or suppress the genes responsible for the cause.

newsystemtoi

Concerns over the repository of the genome sequences:

  • If the genome is sequenced, who should access this?
  • How securely the sequences can be stored away from snooping?
  • How the national database should be made?
  • Would it be easy to handle fastest growing data of sequences?
  • Would this be easy to make available centrally for right access?

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WorkForce Redefined – Collaboration at Healthcare sector and Information Technology level

As the digital revolution gains momentum, doctors, scientists, life sciences and people from different walks of life and other professionals are using machines to be more efficient, powerful, trust worthy and these machines are often now used for getting better decisions and to take on complex tasks.

How machines have gained trust over manual work and efficiency

Augmented devices providing more portability, insights, platform to provide and make available on clicks the huge database of contextual information and research outputs from various industries. Such grounds on cloud facility has indeed helped market research professionals and companies, doctors, scientists, clinical trial process during the entire process. It has helped people from all over the world to click share and connect for advice in quick time to take decisions.

Training of people on machines and technology are equally important

This bullish trend of digitization and evolution of machines into the mainstream of industries from scratch to the end has made this necessary for their people to have adequate knowledge of computer and machines in terms of operating and maintenance of the same.

Life Sciences industries increasing the scope of operations

This growing trend illustrates that how life sciences companies must and should embrace digital way to go beyond the imagination with the goal of meeting the need of society.

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Extensive use of computer learning in providing quality control in genetic database!

Computer learning has gone many folds ahead in coordination with healthcare/clinical technology with a mission of pin pointing many disorders in human body. The same helped generating huge database of sequences, disease impressions, patient’s data etc from around the world. These giant collections of data somewhere has helped too in figuring out many counseling techniques in terms of reducing the incidences of many disorders, biological changes and all. Looking at the bullish nature of the databases, every center in healthcare sector has started shedding lights into this potential field to impart knowledge for the betterment. Many such initiatives have been taken to proof out of this immaculate record when it comes to make sense to the real world.

Stethoscope and globe on a laptop keyboard, focus on stethoscope

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Why Data Science career is exploding these days!

Boom in technology and gadget world has hacked our processes and day to day activities in such a way, that we can’t imagine our day without computer, mobiles and other software that we are dependent for our daily activities on desk. In 2016, lots of predictions have been published about the current need of Data Scientist to analyze the huge chunk of data being generated due to the revolution in technology or the digitization.

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Picture ref: www.bigdatatraining.in

Myriad of sectors and industries call for data scientist and data analyst, for instance healthcare sectors, banking sectors, educational institutes, clinical organizations and many more who are generating data on daily basis in a huge quantity. Many of the industries had never given a thought to utilize their own business data to bring transformation into their system, but now every company at some point of time hires a data scientist to dig into their data to make predictions and other result driven plans out of it and much more in fact. Data Science is a hot position these days where the data scientist works with both data at rest and data in motion and helps firms know the market scenarios and other parameters that they are looking for.

Man Vs Machine!

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Today’s trend in technology and healthcare line…2016 onward would be a fight against many unseen deformities and mutations…

This ain’t new to talk about, that technology and evolution has gone beyond our imagination uptil now. Everyone has hooked badly to the technology and materialistic world. And ofcourse it has cut short times in many of the processes that often used to go longer when it comes to get done with the process. t is amazing how things are going faster and faster. We are living so fast, ain’t we?

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Things have become easy and fast in every part of the world, yeah!, Healthcare industries have boomed with portentous equipment & machines with the help of people who work in collaboration with information technology and this way, it has become easy to come up with solutions, be it into healthcare, mechanical world or any other industrial domain.

Trend now!! Well healthcare is going to face a big challenge in tackling with issues coming up in terms of healthcare problems, deformities, diseases that have been detected for the first time and have no solution right now. It will need another span of time to study the particular disease and issues and to come up with solution.

One disease comes and research starts on that, by the time solution comes, it would start coming with cases in some part of the world with sever deformities and sometimes that is through the same virus but different strain of the virus. Mind, strains designed manually during research and developed due to mutations are horrible in terms of result in human and in animals.

Keywords: Diseases, mutations, issues, deformities, virus, strains

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Ayurveda VS Allopathy!! – How trend is taking “U” turn – Incredible!

As far as I have read about the remedies, things had started with herbs i.e. Ayurveda in ancient times and continued for long. Whereas with the passage of time and evolution. Things changed drastically, Old philosophies and trends went on extinction in mid time. Nobody had ever thought that Allopathic drugs would ever take its way to imbibe the human life completely. Well the Ayurvedic medicine evolved in India almost 5000 years back and is considered to be the world’s oldest healthcare system and indeed it is.  Ayurveda name came from a Sanskrit word that means “science of life”. The holistic formula of Ayurveda strain to create symphony between the body, mind, and spirit, making sure that the balance prevents illness, treats acute conditions, and contributes to a long and healthy life. It has been cited that more than 90% of the population use some form of Ayurvedic treatment or therapy to tune their healthcare system. In India it is taken as a different practice to relieve one from the healthcare issues. Whereas in America it is taken as a complimentary option while many individuals follow massage, meditation and cleansing therapies. And this practice has gained faith from people in tremendous level.

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It has been noticed that, most of the time therapies are intended to tune physical health, mental and spiritual harmony.  Well it is true to much extent that if the mental health is fine, one can have a healthy life.  Ayurveda treats the whole system but not just the organ or system involved.

“The aim of Ayurvedic medicine is to integrate and balance the body, mind, and spirit. This is believed to help prevent illness and promote wellness.” –The National Institutes of Health

I recently had an opportunity to interact with one of the Ayurved practitioner just for my curiosity to know how these formulas work for individual. As, I used to listen a lot and hear about the benefits and all, from person to person. But never had a chance to glance into the same. Being a science student, I was more inclined into recent things that are working well for human being in terms of treating their system. I interacted with folks in day to day life and got to know their reviews about the various remedies available, like they said Allopathic drugs treats but it’s more of kind suppressing the virus or bacteria or any diseased condition. Added the tendency of reoccurrence of the particular suppressed condition or may be other affects that generates as side effects after having long term drugs, is more. Whereas in Ayurveda it’s nothing like that. There is no ground of side effect being noticed yet and not only Asians are sloped towards Ayurved but Americans and people from other parts of the worlds as well are trying Ayurveda and feeling the change.

There are instances where immediate treatment is required in those cases, allopathic rules the world. But when it comes for problems being detected at the beginning and if treated with Ayurved, it treats the ailment from root and the tendency of reoccurrence is negligible.

I feel, people should avoid allopathic treatment if possible, and should go with Ayurvedic remedies right from the detection of the ailment in system.

References:

http://www.elephantjournal.com/2014/12/5-life-changing-lessons-from-ayurveda/

https://prachinayurvedkutir.com/

http://www.webmd.com/balance/guide/ayurvedic-treatments

http://www.elephantjournal.com/2014/12/5-life-changing-lessons-from-ayurveda/

https://www.ayurveda-herbs.com/

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A Short circuit in gene network

Science has developed so far and with the help of available techniques and procedures, it has become quite easy to knock down many disease conditions and other congenital conditions occurring in human lives. Techniques developed till now have really worked well in improving lives. There are many techniques that are being into developing stage and enthusiasts are working hard on it to make it possible to pin down every possible disease and other ailment conditions. One such congenital condition is called, cleft lip and cleft palate. It affects 1 in every 600 children born worldwide (1) and is one of the most commonly occurred congenital deformities. It has been explained and shown the particular gene playing role in sole or in association with other factors playing role in the formation of non-syndromic cleft lip and/or cleft palate. Several genes has been found and sequenced for confirmation and found playing role in formation of different forms of cleft lip and/or cleft format.

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Genomic medicine – A powerful way to tailor healtcare issues on an individual basis

Genomic medicine is a powerful way to tailor all sort of diseases and ailments on an individual basis. This concept is in process since long back. Meanwhile it has resulted into many good therapies among cancer patients and other deadly diseases. It serves a lot in detecting with a real cause and the same can be dealt with available techniques in RNA engineering and DNA mapping. That helps in mapping of the mutations and then the same is treated effectively on an individual basis.

asdfThis starts with the patients genomic information studies. Earlier this used to be a kind of real tough job, but now technology has made it very easy and less expensive too. This helps in designing the more effective drugs to target the affected gene by identifying the genetic factors associated with that particular disease.

This will help a lot in designing individual based medicines and treatments to avoid adverse drug reactions and could possibly the best treatment for anyone.

Till now people have walked around to doctors with their last prescribed medicines and their all history related to their disease. And all costly diagnosing reports along with everything. But now days are not far, in fact it has started in many states but not being highlighted as it still need verification and safety measures to be passed, when people will be walking around to genetic counselors with their gene sequences. And counselor will look into their gene sequences and would compare the same with the genome and let them know the mutations and the possible treatments. Whether this can be treated with the drugs, or genetic engineering etc.

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Is GENOMIC TEST good, if made available in India on large scale?

There is lots of debate on this matter since last few years. It has been made available in US, but not on large scale or on commercial purpose. But it has been kept under observation to analyse its gravity in giving results or in the detection of acute conditions in human.

Yet, these procedures are not allowed in India, as it needs lots of regulations and control procedures. And that is not organized in India on strict grounds. Our government should implement some regulatory acts and pass the same to academic institutions, government hospitals and research institutions, who are studying genomics and trying to know the depth of the mutations in personals.

I support, that if government will allow and keep an eye on the procedure, this will help us in treating and finding out the real time treatments on individual basis. Government should give green flag for safe clinical trials to be conducted to evaluate this in India.

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Our own cell can be engineered to be used as an attacker cell!

There is something new to know in the field of Technology.  It has been tested and satisfactory results have been provided in case of patients suffering with Blood cancers Cells from their own body was taken out and engineered to feed back again to the site where cancer cells were harboring, and populating nonstop. When given gene therapy to the ill patients, it was noticed that patients were out of the danger and free from cancer.

Though, it provided some unsatisfactory results too, but something is better than nothing in this case. As patients were free from cancer even after two years of treatment, and it has paved a challenging and emerging field for others to research and make it more effective.

Hope this way of gene therapy can help us making patients suffering from blood cancers, free from there deadly disease in near future.

This has potential to become the first gene therapy in Unite States. Till now only one gene therapy is approved in Europe for a rare metabolic disease.

Clinical trials and results obtained has given enough results to understand the gravity in this therapy, and hope to make it more friendly and available in case of blood cancer patients to get rid of their illness.

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